Radiesse is a transparent, sterile, injectable gel made of calcium hydroxylapatite particles and the anesthetic Lidocaine. Inject Radiesse (+) 1.5ml with Lidocaine into wrinkles to restore a smoother appearance to aging skin, into areas of facial fat loss to restore volume, or into hands to reduce the looks of visible veins and bones. Only authorized personnel in accordance with local regulations should administer Radiesse.