Cleviel Filler
What is it?
Cleviel Dermal Fillers were recently acquired by PRP (PharmaResearch Products Co., Ltd.) from Aestura, a subsidiary of Amorepacific. Developed with Aestura’s innovative 4L Cross-linking Technology, these fillers feature a high concentration of hyaluronic acid that sustains long-lasting effects while resisting natural biodegradation. With 50 mg/mL HA gel—twice the density of conventional fillers—Cleviel offers excellent facial volumizing and augmentation. The 4L Technology earned the NET (New Excellent Technology) certification by the South Korean Ministry of Health, highlighting its premium quality and technological distinction.
The high viscoelasticity of Cleviel ensures a stable, durable gel structure that delays degradation by hyaluronidase, preserves shape, and prolongs effects while minimizing side effects. The gel’s structure provides exceptional lifting capacity with minimal deformation, preventing migration from the target area. An ergonomic dual-grip syringe allows smooth, precise administration by certified practitioners. The line includes three variants, each with specific lifting capacity and volumizing effect tailored to individual patient needs.
FEATURES
- Cleviel’s 4L Cross-linking Technology hyaluronic acid gel demonstrates four key advantages:
- Low BDDE: Reduced chemical cross-linkers maximize the physical entanglement of the HA gel.
- Low Temperature: Minimizes thermos-degradation of hyaluronic acid.
- Low Swelling: Limited BDDE use reduces side effects such as swelling and inflammation, delivering precise results.
- Long Duration: High concentration and compact cross-linking ensure prolonged effectiveness.
FORMULATION
The fillers contain high-density hyaluronic acid gel that maintains structure after injection, prolonging desired outcomes with minimal deformation. Each 1 mL pre-filled syringe contains 50 mg/mL cross-linked HA.
BENEFITS
- Cleviel has undergone rigorous clinical testing to confirm safety and efficacy. Key benefits include:
- Visible wrinkle improvement, with full effects seen up to 24 months
- High satisfaction rate with minimal side effects
- Ideal for augmentation and volumizing depressed facial areas
- Precise contouring and volumizing capabilities
- Varying degrees of lifting for targeted treatments
- Temporary improvement of adult facial wrinkles through non-invasive treatment
DURATION OF EFFECT:
Thanks to the high concentration, effects can last 12–15 months, with immediate visible improvements and full results developing over 24 months.
PRODUCT RANGE
CLEVIEL CONTOUR
- Composition: 50 mg/mL HA
- Best Feature: Clear line gel filler
- Indications: Facial contouring
- Applications: Nose contouring, jawline shaping
- Injection Depth: Mid to deep dermis
- Needle Size: 26G ½’ (2 per package)
- Duration: Over 12 months
- Packaging: 1 × 1 mL pre-filled syringe
- Storage: 2–25°C, avoid freezing, heating, sunlight, or pressure
- Shelf Life: 24 months
CLEVIEL VOLUME
- Composition: 50 mg/mL HA, 0.3% Lidocaine
- Best Feature: Stable, structured HA gel
- Indications: Deep lifting
- Applications: Glabella, nasolabial folds, marionette lines, hollow cheeks, forehead wrinkles
- Injection Depth: Deep dermis to subcutaneous layer
- Needle Size: 2 × 26G ½’, 2 × 25G 5/8’
- Duration: Over 12 months
- Packaging: 2 × 1 mL pre-filled syringes
- Storage: 2–25°C, avoid freezing, heating, sunlight, or pressure
- Shelf Life: 24 months
CLEVIEL PRIME
- Composition: 33 mg/mL HA, 0.3% Lidocaine
- Best Feature: Produces 3D volume in depressed areas
- Indications: Volumizing and facial balance
- Applications: Jawline, chin, cheeks
- Injection Depth: Subcutaneous layer
- Needle Size: 27G ½’ (4 per package)
- Duration: Over 12 months
- Packaging: 2 × 1 mL pre-filled syringes
- Storage: 2–25°C, avoid freezing, heating, sunlight, or pressure
- Shelf Life: 24 months


